Trial intelligence / Profile preview

RN5681 in Healthy Volunteers

NCT07347678Phase 1Recruiting

Sponsor
Ikaria
Start
Mar 2026
Primary completion
Feb 2027
Modality
Conjugated siRNA, Chemically Modified siRNA
Countries
1
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Overview

Phase 1, randomised trial in hypercholesterolemia comparing RN5681 with Placebo (2 arms). Primary endpoints: Safety and tolerability of subcutaneously administered RN5681 at Day 180 and Metabolic markers of efficacy at Day 180. Started Mar 2026; status: recruiting.

02

Drugs

RN5681
03

Conditions

hypercholesterolemia

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