Trial intelligence / Profile preview

DDI Study of Vanzacaftor/Tezacaftor/Deutivacaftor and Rosuvastatin in Healthy Subjects

NCT07349394Phase 1Completed

Sponsor
Vertex Pharmaceuticals
Start
Jan 2026
Primary completion
Feb 2026
Modality
Small Molecules
Countries
1
01

Overview

Phase 1, open-label, single-arm trial of vanzacaftor, tezacaftor and deutivacaftor in cystic fibrosis (CF), sponsored by Vertex Pharmaceuticals. Primary endpoints: Maximum Observed Concentration of Rosuvastatin and Area Under the Concentration Time-curve of Rosuvastatin. Started Jan 2026; status: completed.

02

Drugs

vanzacaftortezacaftordeutivacaftor
03

Conditions

cystic fibrosis (CF)

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