Trial intelligence / Profile preview

Ziftomenib and Mezigdomide in Relapsed or Refractory AML

NCT07355335Phase 1Recruiting

Sponsor
Massachusetts General Hospital
Start
Sep 2026
Primary completion
Jul 2027
Modality
Molecular Glues
Countries
1
01

Overview

Phase 1, open-label, single-arm trial of ziftomenib and mezigdomide in acute myeloid leukemia (AML), sponsored by Massachusetts General Hospital. Primary endpoints: Incidence of Treatment-Emergent Adverse Events at 2 years and Recommended Phase 2 Dose at 48 weeks. Started Sep 2026; status: recruiting.

02

Drugs

ziftomenibmezigdomide
03

Conditions

acute myeloid leukemia (AML)

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