Trial intelligence / Profile preview

CLS-015 and CAR-T in Large B-Cell Lymphoma

NCT07361224Phase 1Recruiting

Sponsor
Tel Aviv Sourasky Medical Center
Start
May 2026
Primary completion
Feb 2027
Modality
Therapeutic Enzymes
Countries
1
01

Overview

Phase 1, open-label, single-arm trial of dornase alfa in diffuse large B-cell lymphoma (DLBCL), sponsored by Tel Aviv Sourasky Medical Center. Primary endpoint: Safety and tolerability of CLS-015 in combination with anti CD19 CAR T therapy at 2 years. Started May 2026; status: recruiting.

02

Drugs

dornase alfa
03

Conditions

diffuse large B-cell lymphoma (DLBCL)

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