Trial intelligence / Profile preview

IMPACT-MACS: Adrenalectomy vs Semaglutide in Mild Autonomous Cortisol Secretion

NCT07361874Recruiting

Sponsor
UT Southwestern Medical Center
Start
Mar 2026
Primary completion
May 2030
Modality
Peptides, Recombinant Proteins and Enzymes
Countries
1
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Overview

Randomised, open-label trial of semaglutide in Autonomous Cortisol Secretion (ACS) (3 arms), sponsored by UT Southwestern Medical Center. Primary endpoint: Change in Insulin Sensitivity (M-value) at 26 weeks. Started Mar 2026; status: recruiting.

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Drugs

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Conditions

Autonomous Cortisol Secretion (ACS)

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