Trial intelligence / Profile preview

TROP2 CAR-NK Cells and Belzutifan in Pancreatic Cancer

NCT07377526Phase 2Suspended

Sponsor
University of Texas MD Anderson Cancer Center
Start
May 2026
Primary completion
Mar 2028
Modality
Gene Editing, Gene Silencing, Lymphokine-Activated Killer Cells
Countries
1
01

Overview

Phase 2, open-label, single-arm trial of TROP2 CAR/IL-15 TGFBR2 KO NK cells in pancreatic cancer (PC), sponsored by University of Texas MD Anderson Cancer Center. Primary endpoints: Adverse Events at 1 year and Dose-Limiting Toxicity at 1 year. Started May 2026; status: suspended.

02

Drugs

TROP2 CAR/IL-15 TGFBR2 KO NK cells
03

Conditions

pancreatic cancer (PC)

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