Trial intelligence / Profile preview

CD19/BAFF-R in Vivo CAR-T Cell Therapy Targeting Relapsed/Refractory B Cell Acute Leukemia/Malignant Lymphoma

NCT07383233Phase 1Not yet recruiting

Sponsor
Qideng Pharmaceutical
Start
Jun 2026
Primary completion
May 2028
Modality
Gene Editing, Gene Silencing, CAR-T Cells
01

Overview

Phase 1, open-label, single-arm trial of CD19/BAFF-R in vivo CAR-T in B cell acute lymphoblastic leukemia (B-ALL) and B cell lymphoma, sponsored by Qideng Pharmaceutical. Primary endpoints: Safety of CD19/BAFF-R in vivo CAR-T cell therapy at 1 month and Efficacy of CD19/BAFF-R in vivo CAR-T cell therapy at 3 months. Planned start Jun 2026; status: not yet recruiting.

02

Drugs

CD19/BAFF-R in vivo CAR-T
03

Conditions

B cell acute lymphoblastic leukemia (B-ALL)B cell lymphoma

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