Trial intelligence / Profile preview

QT-019C in Relapsed/Refractory Neurological Autoimmune Diseases

NCT07392528Phase 1Not yet recruiting

Sponsor
Tianjin Huanhu Hospital
Start
Mar 2026
Primary completion
Jun 2027
Modality
CAR-T Cells
Countries
1
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Overview

Phase 1, open-label, single-arm trial of anti-CD19/BCMA CAR T-cells in Neuromyelitis Optica Spectrum Disorder (NMOSD), multiple sclerosis (MS), myasthenia gravis (MG) and 2 more, sponsored by Tianjin Huanhu Hospital. Primary endpoints: Dose-Limiting Toxicity at 28 days and Adverse Events at 90 days. Planned start Mar 2026; status: not yet recruiting.

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Drugs

anti-CD19/BCMA CAR T-cells
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Conditions

Neuromyelitis Optica Spectrum Disorder (NMOSD)multiple sclerosis (MS)myasthenia gravis (MG)Autoimmune Encephalitis (AE)chronic inflammatory demyelinating polyradiculoneuropathy (CIDP)

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