Trial intelligence / Profile preview

PF-08634404 in Combination With Chemotherapy in Advanced Gastric, Gastroesophageal Junction, or Esophageal Adenocarcinoma

NCT07392892Phase 3Recruiting

Sponsor
Pfizer
Start
May 2026
Primary completion
Jul 2031
Modality
Bispecific Antibodies
Countries
10
01

Overview

Phase 3, randomised trial of PF-08634404 in gastric adenocarcinoma, gastroesophageal junction adenocarcinoma and esophageal adenocarcinoma (EAC) (3 arms), sponsored by Pfizer. Primary endpoints: Objective Response Rate at 4 years, Treatment-Emergent Adverse Events at 4 years and 2 more. Started May 2026; status: recruiting.

02

Drugs

PF-08634404
03

Conditions

gastric adenocarcinomagastroesophageal junction adenocarcinomaesophageal adenocarcinoma (EAC)

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