Trial intelligence / Profile preview

CBG131 CAR-T in CLDN18.2-Positive Advanced Gastric and Pancreatic Cancer

NCT07394205Phase 1Not yet recruiting

Sponsor
The First Affiliated Hospital of Wenzhou Medical University
Start
Sep 2026
Primary completion
Mar 2027
Modality
Gene Editing, Gene Silencing, CAR-T Cells
Countries
1
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Overview

Phase 1, open-label, single-arm trial of CBG131 in gastric cancer (GC) and pancreatic cancer (PC), sponsored by The First Affiliated Hospital of Wenzhou Medical University. Primary endpoints: Incidence and Grading of Adverse Events and Serious Adverse Events at 15 years, Incidence and Determination of Dose-Limiting Toxicity at 28 days and 1 more. Planned start Sep 2026; status: not yet recruiting.

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Drugs

CBG131
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Conditions

gastric cancer (GC)pancreatic cancer (PC)

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