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COVHIC003: Controlled Human Infection Model for SARS-CoV-2 Omicron EG.5.1

NCT07397455Phase 1Recruiting

Sponsor
Imperial College London
Start
Jul 2026
Primary completion
Dec 2027
Countries
1
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Overview

Phase 1, open-label trial in coronavirus disease 2019 (COVID-19) (4 arms), sponsored by Imperial College London. Primary endpoints: Safety and human clinical response to intranasal challenge at 28 days and Selection of the SARS-CoV-2 Omicron EG.5.1 dose(s) required to induce laboratory confirmed upper respiratory tract infection at 10 days. Started Jul 2026; status: recruiting.

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Conditions

coronavirus disease 2019 (COVID-19)

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