Trial intelligence / Profile preview

Phase 1, Single Ascending Dose Study of Subcutaneous BW-50218 in Healthy Participants

NCT07401472Phase 1Active, not recruiting

Sponsor
Shanghai Argo Biopharmaceutical Co., Ltd.
Start
Mar 2026
Primary completion
Jun 2027
Modality
Conjugated siRNA, Chemically Modified siRNA
Countries
1
01

Overview

Phase 1, randomised, double-blind trial of BW-50218 in transthyretin amyloidosis (ATTR) (7 arms), sponsored by Shanghai Argo Biopharmaceutical Co., Ltd. Primary endpoints: Incidence and Severity of Adverse Events (AEs) and Serious Adverse Events (SAEs) at Day 360, Change from Baseline in Clinical Laboratory Test Results at Day 360 and 3 more. Started Mar 2026; status: active, not recruiting.

02

Drugs

BW-50218
03

Conditions

transthyretin amyloidosis (ATTR)

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