Trial intelligence / Profile preview

SELECT-CAR-NK in Advanced Solid Tumors

NCT07410494Phase 2Recruiting

Sponsor
Essen BioTech
Start
Feb 2026
Primary completion
Dec 2027
Modality
Lymphokine-Activated Killer Cells, CAR-NK Cells
Countries
1
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Overview

Phase 2, open-label trial of EB-SELECT Single-Target CAR-NK Cells and EB-SELECT Dual-Target CAR-NK Cells in solid tumor, breast cancer, non-small cell lung cancer (NSCLC) and 7 more (2 arms), sponsored by Essen BioTech. Primary endpoints: Adverse Events at 28 days and Dose-Limiting Toxicities at 28 days. Started Feb 2026; status: recruiting.

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Drugs

EB-SELECT Single-Target CAR-NK CellsEB-SELECT Dual-Target CAR-NK Cells
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Conditions

solid tumorbreast cancernon-small cell lung cancer (NSCLC)colorectal cancer (CRC)prostate cancer (PCa)

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