Trial intelligence / Profile preview

Safety and Immunogenicity of rVSV∆G-MARV-GP Vaccine in Healthy Adults

NCT07425821Phase 1Active, not recruiting

Sponsor
International AIDS Vaccine Initiative
Start
Mar 2026
Primary completion
Apr 2027
Modality
Live Vector Vaccines
Countries
1
01

Overview

Phase 1, randomised, single-blind trial in Marburg virus disease (MVD) comparing rVSV∆G-MARV-GP with Placebo/Diluent (2 arms). Primary endpoints: Safety and tolerability: solicited reactogenicity at 14 days, Safety and tolerability: unsolicited reactogenicity at 28 days and 1 more. Started Mar 2026; status: active, not recruiting.

02

Drugs

rVSVΔG-MARV (Angola) GP
03

Conditions

Marburg virus disease (MVD)

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