Trial intelligence / Profile preview

CS0159 DDI and Food Effect Study in Healthy Adults

NCT07429331Phase 1Completed

Sponsor
Cascade Pharmaceuticals
Start
Mar 2026
Primary completion
Mar 2026
Modality
Small Molecules
Countries
1
01

Overview

Phase 1, randomised, open-label trial of linafexor in Nonalcoholic steatohepatitis (NASH), primary biliary cholangitis (PBC) and Primary Sclerosing Cholangitis (PSC) (3 arms), sponsored by Cascade Pharmaceuticals. Primary endpoints: Maximum Plasma Concentration at Day 9, Area Under the Curve from Time Zero to Last Quantifiable Concentration at Day 9 and 4 more. Started Mar 2026; status: completed.

02

Drugs

linafexor
03

Conditions

Nonalcoholic steatohepatitis (NASH)primary biliary cholangitis (PBC)Primary Sclerosing Cholangitis (PSC)

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