Trial intelligence / Profile preview

Dexmedetomidine and Glymphatic Function in Healthy Older Adults

NCT07432997Phase 2Completed

Sponsor
Applied Cognition
Start
Dec 2023
Primary completion
Sep 2024
Modality
Small Molecules
Countries
1
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Overview

Phase 2, randomised, double-blind trial of dexmedetomidine in Alzheimer's disease (AD) (4 arms), sponsored by Applied Cognition. Primary endpoints: Mean change from baseline in plasma Aβ42/Aβ40 ratio following dexmedetomidine treatment at 4 hours, Mean change from baseline in plasma Aβ42/Aβ40 ratio following dexmedetomidine and midodrine treatment at 4 hours and 2 more. Started Dec 2023; status: completed.

02

Drugs

dexmedetomidine
03

Conditions

Alzheimer's disease (AD)

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