Trial intelligence / Profile preview

AFN50 in Autoimmune Diseases

NCT07448298Phase 1Withdrawn

Sponsor
Beijing Boren Hospital
Start
Mar 2026
Primary completion
Apr 2026
Modality
Gene Editing, Gene Silencing, Gene Addition/Replacement
Countries
1
01

Overview

Phase 1, open-label, single-arm trial of AFN50 in systemic lupus erythematosus (SLE), Sjögren's syndrome, myasthenia gravis (MG) and 3 more, sponsored by Beijing Boren Hospital. Primary endpoint: Adverse Events at 3 months. Planned start Mar 2026; status: withdrawn.

02

Drugs

AFN50
03

Conditions

systemic lupus erythematosus (SLE)Sjögren's syndromemyasthenia gravis (MG)systemic sclerosis (SSc)idiopathic inflammatory myopathy (IIM)

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