Trial intelligence / Profile preview

KST-6051 in Advanced or Metastatic Solid Tumors With a KRAS Mutation

NCT07458347Phase 1Recruiting

Sponsor
Kestrel Therapeutics
Start
Apr 2026
Primary completion
Apr 2028
Modality
Small Molecules
Countries
1
01

Overview

Phase 1, open-label trial of KST-6051 in solid tumor, non-small cell lung cancer (NSCLC), pancreatic ductal adenocarcinoma (PDAC) and 1 more (13 arms), sponsored by Kestrel Therapeutics. Primary endpoints: Dose-limiting Toxicities at 3 weeks, Treatment-emergent Adverse Events at 2 years and 2 more. Started Apr 2026; status: recruiting.

02

Drugs

KST-6051
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Conditions

solid tumornon-small cell lung cancer (NSCLC)pancreatic ductal adenocarcinoma (PDAC)colorectal cancer (CRC)

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