Trial intelligence / Profile preview

First-generation vs Third-generation EGFR TKIs for Advanced NSCLC With EGFR 19delins Mutation

NCT07458919Phase 1Not yet recruiting

Sponsor
900th Hospital of Joint Logistics Support Force of PLA
Start
Mar 2026
Primary completion
Oct 2030
Modality
Orthosteric Ligands
01

Overview

Phase 1, randomised trial of icotinib and gefitinib in non-small cell lung cancer (NSCLC) (2 arms), sponsored by 900th Hospital of Joint Logistics Support Force of PLA. Primary endpoint: Progression-Free Survival at 60 months. Planned start Mar 2026; status: not yet recruiting.

02

Drugs

icotinibgefitinib
03

Conditions

non-small cell lung cancer (NSCLC)

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