Trial intelligence / Profile preview

PRT12396 in Polycythemia Vera and Myelofibrosis

NCT07469891Phase 1Recruiting

Sponsor
Prelude Therapeutics
Start
Apr 2026
Primary completion
Apr 2028
Modality
Small Molecules
Countries
5
01

Overview

Phase 1, open-label trial of PRT12396 in polycythemia vera (PV) and myelofibrosis (MF) (2 arms), sponsored by Prelude Therapeutics. Primary endpoints: Dose Limiting Toxicity at 4 weeks, Incidence and severity of Adverse events at 2 years and 2 more. Started Apr 2026; status: recruiting.

02

Drugs

PRT12396
03

Conditions

polycythemia vera (PV)myelofibrosis (MF)

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