Trial intelligence / Profile preview

MEND-IT II

NCT07472868Phase 3Recruiting

Sponsor
J.W.A. Burger
Start
Mar 2026
Primary completion
Mar 2030
Modality
DNA Intercalators/Alkylators, Irreversible Covalent Inhibitors, Orthosteric Ligands
Countries
1
01

Overview

Phase 3, randomised, open-label trial of FOLFIRINOX in locally advanced rectal cancer (LARC) (3 arms), sponsored by J.W.A. Burger. Primary endpoint: Pathological Complete Response or Sustained Clinical Complete Response at 1 year. Started Mar 2026; status: recruiting.

02

Drugs

FOLFIRINOX
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Conditions

locally advanced rectal cancer (LARC)

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