Trial intelligence / Profile preview

SCRT Followed by NALIRIXELOX and Sintilimab as Total Neoadjuvant Therapy in High-Risk Locally Advanced Rectal Cancer

NCT07474103Recruiting

Start
Nov 2025
Primary completion
Mar 2028
Modality
Small Molecules, Lipid-based Nanoparticles, Monoclonal Antibodies
Countries
1
01

Overview

Open-label, single-arm trial of sintilimab and nanoliposomal irinotecan in rectal cancer. Primary endpoint: Complete Response Rate at 6 months. Started Nov 2025; status: recruiting.

02

Drugs

sintilimabnanoliposomal irinotecan
03

Conditions

rectal cancer

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