Trial intelligence / Profile preview

ML261 in Relapsed/Refractory Small Cell Lung Cancer or Select Neuroendocrine Carcinomas

NCT07488923Phase 1Recruiting

Start
Jun 2026
Primary completion
Mar 2028
Modality
Gene Editing, Gene Silencing, CAR-T Cells
Countries
1
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Overview

Phase 1, open-label, single-arm trial of ML261 in small cell lung cancer (SCLC), extrapulmonary neuroendocrine carcinoma (EPNEC), gastroenteropancreatic neuroendocrine carcinoma (GEP-NEC) and 1 more. Primary endpoint: Dose-Limiting Toxicities at 28 days. Started Jun 2026; status: recruiting.

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Drugs

ML261
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Conditions

small cell lung cancer (SCLC)extrapulmonary neuroendocrine carcinoma (EPNEC)gastroenteropancreatic neuroendocrine carcinoma (GEP-NEC)neuroendocrine prostate cancer (NEPC)

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