Trial intelligence / Profile preview

Low-intensity Chemotherapy Combined With Targeted-Immunotherapy for Newly Diagnosed Ph+ ALL

NCT07493161Recruiting

Sponsor
Institute of Hematology and Blood Diseases Hospital
Start
Apr 2026
Primary completion
Mar 2028
Modality
Small Molecules
Countries
1
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Overview

Randomised, open-label trial of venetoclax and inotuzumab ozogamicin in Acute lymphoblastic leukemia, Philadelphia chromosome positive (2 arms), sponsored by Institute of Hematology and Blood Diseases Hospital. Primary endpoints: Rate of BCR::ABL1 <=0.01% at 90 days and Modified Event-Free Survival up to 2 years. Started Apr 2026; status: recruiting.

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Drugs

venetoclaxinotuzumab ozogamicin
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Conditions

Acute lymphoblastic leukemia, Philadelphia chromosome positive

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