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FLAME: Intracalvariosseous vs Intravenous Antibiotics in Bacterial Meningitis
NCT07495150Not yet recruiting
- Start
- Apr 2026
- Primary completion
- Apr 2027
- Modality
- Cyclic Peptides, Antimicrobial Peptides, Orthosteric Ligands
- Countries
- 1
01
Overview
Randomised, open-label trial of polymyxin B, tigecycline and vancomycin in bacterial meningitis (2 arms). Primary endpoint: Overall effective rate at 14 days. Planned start Apr 2026; status: not yet recruiting.
02
Drugs
polymyxin Btigecyclinevancomycin
03
Conditions
bacterial meningitis
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