Trial intelligence / Profile preview

Revumenib for Maintenance Therapy After HSCT in Pediatric Patients With Acute Leukemia

NCT07498465Phase 1Withdrawn

Sponsor
Children's Oncology Group
Start
Sep 2026
Primary completion
Nov 2028
Modality
Small Molecules
01

Overview

Phase 1, open-label, single-arm trial of revumenib in acute lymphoblastic leukemia (ALL), acute myeloid leukemia (AML) and mixed phenotype acute leukemia (MPAL), sponsored by Children's Oncology Group. Primary endpoints: Maximum Tolerated Dose, Recommended Phase 2 Dose and 4 more. Planned start Sep 2026; status: withdrawn.

02

Drugs

revumenib
03

Conditions

acute lymphoblastic leukemia (ALL)acute myeloid leukemia (AML)mixed phenotype acute leukemia (MPAL)

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