Trial intelligence / Profile preview

AMAZE 6: NNC0487-0111 in Overweight/Obesity and Knee Osteoarthritis

NCT07509307Phase 3Recruiting

Sponsor
Novo Nordisk
Start
Apr 2026
Primary completion
Aug 2028
Modality
Peptides, Small Molecules
Countries
11
01

Overview

Phase 3, randomised, double-blind trial in obesity, Overweight and osteoarthritis (OA) comparing NNC0487-0111 with Placebo (2 arms). Primary endpoints: Relative change in body weight at 80 weeks and Change in Western Ontario and McMaster Universities Osteoarthritis Index Numerical Rating Scale (NRS) 3.1 (24-hour) (WOMAC) pain score at 80 weeks. Started Apr 2026; status: recruiting.

02

Drugs

amycretin
03

Conditions

obesityOverweightosteoarthritis (OA)

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