Trial intelligence / Profile preview

Mirdametinib Alone or With Radiotherapy for NF1-Altered High-Grade Glioma

NCT07521657Phase 2Not yet recruiting

Sponsor
University of Alabama at Birmingham
Start
Jan 2027
Primary completion
Jan 2031
Modality
Small Molecules
Countries
1
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Overview

Phase 2, open-label trial of mirdametinib in glioblastoma (GBM), glioma and high-grade astrocytoma with piloid features (HGAP) (3 cohorts), sponsored by University of Alabama at Birmingham. Primary endpoint: Radiographic Response by RANO 2.0 Criteria at 18 months. Planned start Jan 2027; status: not yet recruiting.

02

Drugs

mirdametinib
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Conditions

glioblastoma (GBM)gliomahigh-grade astrocytoma with piloid features (HGAP)

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