Trial intelligence / Profile preview

ADAPT-HEM: Biomarker-Selected Dual-Target CAR-T in R/R Hematologic Malignancies

NCT07523555Phase 2Recruiting

Sponsor
Biotech Pharmaceutical
Start
Mar 2026
Primary completion
Mar 2027
Countries
1
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Overview

Phase 2, open-label trial in acute lymphoblastic leukemia (ALL), non-Hodgkin lymphoma (NHL), chronic lymphocytic leukemia (CLL) and 8 more (8 arms), sponsored by Biotech Pharmaceutical. Primary endpoints: Dose-limiting toxicities at 28 days and Cytokine release syndrome at 28 days. Started Mar 2026; status: recruiting.

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Conditions

acute lymphoblastic leukemia (ALL)non-Hodgkin lymphoma (NHL)chronic lymphocytic leukemia (CLL)small lymphocytic lymphoma (SLL)multiple myeloma (MM)

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