Trial intelligence / Profile preview

REBEL: Radiation Followed by Bispecific Antibody Therapy for R/R DLBCL

NCT07528352Phase 1Recruiting

Sponsor
University of Utah
Start
Jun 2026
Primary completion
Jun 2030
Modality
Antibody Conjugates, Bispecific Antibodies, Recombinant Proteins and Enzymes
Countries
1
01

Overview

Phase 1, open-label, single-arm trial of epcoritamab and glofitamab in diffuse large B-cell lymphoma (DLBCL), sponsored by University of Utah. Primary endpoint: Rate of Cytokine Release Syndrome and Immune Effector Cell-Associated Neurotoxicity Syndrome at 18 months. Started Jun 2026; status: recruiting.

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Drugs

epcoritamabglofitamab
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Conditions

diffuse large B-cell lymphoma (DLBCL)

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