Trial intelligence / Profile preview

ZE74-0282 in Select JAK2 V617F Mutated Hematologic Disorders

NCT07529951Phase 1Not yet recruiting

Sponsor
Eilean Therapeutics
Start
May 2026
Primary completion
Sep 2028
Modality
Small Molecules
01

Overview

Phase 1, open-label trial of ZE74-0282 in polycythemia vera (PV) and myelofibrosis (MF) (8 arms), sponsored by Eilean Therapeutics. Primary endpoints: Recommended Phase 2 Dose at 5 months and Dose-Limiting Toxicities. Planned start May 2026; status: not yet recruiting.

02

Drugs

ZE74-0282
03

Conditions

polycythemia vera (PV)myelofibrosis (MF)

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