Trial intelligence / Profile preview

BAY 3771249 as Monotherapy or in Combination With Cetuximab in Advanced/Metastatic Colorectal Cancer With KRAS G12D Mutation

NCT07535112Phase 1Recruiting

Sponsor
Bayer
Start
Apr 2026
Primary completion
Jul 2029
Modality
Covalent Small Molecules
Countries
10
01

Overview

Phase 1, randomised, open-label trial of KQB548 in colorectal adenocarcinoma (2 arms), sponsored by Bayer. Primary endpoints: Change from baseline in laboratory test results at 2 years, Change from baseline in vital signs: Blood pressure at 2 years and 8 more. Started Apr 2026; status: recruiting.

02

Drugs

KQB548
03

Conditions

colorectal adenocarcinoma

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