Trial intelligence / Profile preview

Ivonescimab + Chemotherapy + SRS for NSCLC Brain Metastases

NCT07535463Phase 2Recruiting

Sponsor
Memorial Sloan Kettering Cancer Center
Start
Apr 2026
Primary completion
Apr 2028
Modality
Antibody Conjugates, Bispecific Antibodies, Monoclonal Antibodies
Countries
1
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Overview

Phase 2, open-label, single-arm trial of ivonescimab in non-small cell lung cancer (NSCLC), sponsored by Memorial Sloan Kettering Cancer Center. Primary endpoints: Recommended Phase 2 Dose at 21 days and Intracranial Progression-Free Survival at 3 months. Started Apr 2026; status: recruiting.

02

Drugs

ivonescimab
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Conditions

non-small cell lung cancer (NSCLC)

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