Trial intelligence / Profile preview

Relative Bioavailability of Two Evolocumab Drug Products in Healthy Participants

NCT07545226Phase 1Completed

Sponsor
Amgen
Start
Apr 2026
Primary completion
Sep 2026
Modality
Monoclonal Antibodies
Countries
1
01

Overview

Phase 1, randomised, open-label trial of evolocumab in hypercholesterolemia (2 arms), sponsored by Amgen. Primary endpoints: Area Under the Concentration-time Curve from Time 0 Extrapolated to Infinity at Day 64, Area Under the Concentration-time Curve from Time 0 to Time of Last Quantifiable Concentration at Day 64 and 1 more. Started Apr 2026; status: completed.

02

Drugs

evolocumab
03

Conditions

hypercholesterolemia

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