Trial intelligence / Profile preview

Neoadjuvant Ficerafusp Alfa, Pembrolizumab, and SBRT for Locally Advanced HNSCC

NCT07552558Phase 2Not yet recruiting

Sponsor
Washington University School of Medicine
Start
Nov 2026
Primary completion
Jan 2029
Modality
Prophylactic Vaccines, Bispecific Antibodies, Therapeutic Vaccines
Countries
1
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Overview

Phase 2, open-label trial of ficerafusp alfa in head and neck squamous cell carcinoma (HNSCC) (5 arms), sponsored by Washington University School of Medicine. Primary endpoints: Maximum Tolerated Dose at 7 weeks and Pathologic Complete Response at 7 weeks. Planned start Nov 2026; status: not yet recruiting.

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Drugs

ficerafusp alfa
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Conditions

head and neck squamous cell carcinoma (HNSCC)

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