Trial intelligence / Profile preview

LM-302 and S-1 Plus Paclitaxel +/- Cadonilimab in Claudin 18.2-positive Gastric Cancer

NCT07556640Phase 2Recruiting

Sponsor
Ruijin Hospital
Start
Apr 2026
Primary completion
Apr 2028
Modality
Monoclonal Antibodies, Bispecific Antibodies, Antibody-Drug Conjugates (ADCs)
Countries
1
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Overview

Phase 2, randomised, open-label trial of tpx-4589 and cadonilimab in gastric adenocarcinoma and gastroesophageal junction adenocarcinoma (2 arms), sponsored by Ruijin Hospital. Primary endpoint: 1-year survival rate at 24 months. Started Apr 2026; status: recruiting.

02

Drugs

tpx-4589cadonilimab
03

Conditions

gastric adenocarcinomagastroesophageal junction adenocarcinoma

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