Trial intelligence / Profile preview

BRII-5395, Sintilimab, and Bevacizumab in Advanced HBV-Related Hepatocellular Carcinoma

NCT07557251Phase 1Recruiting

Sponsor
Cancer Institute and Hospital, Chinese Academy of Medical Sciences
Start
Aug 2026
Primary completion
Dec 2028
Countries
1
01

Overview

Phase 1, open-label trial of BRII-5395 in hepatocellular carcinoma (HCC) (2 arms), sponsored by Cancer Institute and Hospital, Chinese Academy of Medical Sciences. Primary endpoints: Dose-Limiting Toxicities at 30 days, Adverse Events at 30 days and 1 more. Started Aug 2026; status: recruiting.

02

Drugs

BRII-5395
03

Conditions

hepatocellular carcinoma (HCC)

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