Trial intelligence / Profile preview

Pucotenlimab + Becotatug Vedotin in locally advanced resectable HNSCC

NCT07586124Phase 2Recruiting

Sponsor
Lepu Biopharma Co., Ltd.
Start
Jul 2026
Primary completion
Dec 2027
Modality
Monoclonal Antibodies, Antibody-Drug Conjugates (ADCs)
Countries
1
01

Overview

Phase 2, randomised, double-blind trial in head and neck squamous cell carcinoma (HNSCC) comparing Becotatug Vedotin + Pucotenlimab with Placebo + Pucotenlimab (2 arms). Primary endpoint: Major Pathological Response Rate up to 8 weeks. Started Jul 2026; status: recruiting.

02

Drugs

becotatug vedotin
03

Conditions

head and neck squamous cell carcinoma (HNSCC)

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