Trial intelligence / Profile preview

YOLT-203 in Primary Hyperoxaluria Type 1

NCT07587021Phase 2Recruiting

Sponsor
YolTech Therapeutics
Start
Sep 2026
Primary completion
Aug 2027
Modality
Gene Silencing, CRISPR-Cas9, Lipid-based Nanoparticles
Countries
1
01

Overview

Phase 2, randomised, double-blind trial in Primary Hyperoxaluria Type 1 (PH1) comparing YOLT-203 First with Placebo First (2 arms). Primary endpoint: Percent Change From Baseline in 24-Hour Urinary Oxalate (BSA-Corrected). Started Sep 2026; status: recruiting.

02

Drugs

YOLT-203
03

Conditions

Primary Hyperoxaluria Type 1 (PH1)

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