Trial intelligence / Profile preview

Effect of Ulonivirine on Methadone Pharmacokinetics

NCT07595263Phase 1Recruiting

Sponsor
Merck & Co.
Start
Aug 2026
Primary completion
Jan 2027
Modality
Small Molecules
Countries
1
01

Overview

Phase 1, open-label, single-arm trial of ulonivirine in human immunodeficiency virus infection (HIV), sponsored by Merck & Co. Primary endpoints: Dose-Normalized Area Under the Plasma Concentration Time Curve From 0-24 Hours Postdose of R-Methadone and Dose-Normalized Area Under the Plasma Concentration Time Curve From 0-24 Hours Postdose of S-Methadone. Started Aug 2026; status: recruiting.

02

Drugs

ulonivirine
03

Conditions

human immunodeficiency virus infection (HIV)

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