Trial intelligence / Profile preview

SHIELD: Valacyclovir, Celecoxib, and Paxlovid in Long COVID

NCT07597902Phase 2Recruiting

Sponsor
Icahn School of Medicine at Mount Sinai
Start
Oct 2026
Primary completion
Jun 2028
Modality
Orthosteric Ligands, Metabolically Activated Prodrugs
Countries
1
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Overview

Phase 2, randomised, double-blind trial of valaciclovir, celecoxib oral solution and Nirmatrelvir in post-COVID-19 condition (PCC) (2 arms), sponsored by Icahn School of Medicine at Mount Sinai. Primary endpoint: EuroQol Five-Dimensional Health Questionnaire Visual Analogue Scale at 20 weeks. Started Oct 2026; status: recruiting.

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Drugs

valaciclovircelecoxib oral solutionNirmatrelvir
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Conditions

post-COVID-19 condition (PCC)

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