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Ibuprofen, Nitrofurantoin, or Calcium Hydroxide as Intracanal Medicaments in Root Canal Treatment
NCT07603934Phase 1Recruiting
- Sponsor
- Cairo University
- Start
- Dec 2025
- Primary completion
- Feb 2027
- Modality
- Metabolically Activated Prodrugs
- Countries
- 1
01
Overview
Phase 1, randomised, double-blind trial of ibuprofen and nitrofurantoin in pulp necrosis and apical periodontitis (AP) (3 arms), sponsored by Cairo University. Primary endpoint: Intensity of Postoperative pain at 72 hours. Started Dec 2025; status: recruiting.
02
Drugs
ibuprofennitrofurantoin
03
Conditions
pulp necrosisapical periodontitis (AP)
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