Trial intelligence / Profile preview

SOLVE-01: Experimental vs Authorized SARS-CoV-2 Vaccines as Booster in Healthy Adults

NCT07605520Phase 1Recruiting

Sponsor
ANRS
Start
May 2026
Primary completion
May 2028
Modality
Vaccines & Immunotherapeutics, Fc-Fusion Proteins
Countries
2
01

Overview

Phase 1, randomised, open-label trial of CD40.RBDv and CD40 Pan-CoV in coronavirus disease 2019 (COVID-19) (4 arms), sponsored by ANRS. Primary endpoints: Proportion of participants without any grade 3 or 4 adverse event and Geometric mean titers of neutralizing antibodies at Week 48. Started May 2026; status: recruiting.

02

Drugs

CD40.RBDvCD40 Pan-CoV
03

Conditions

coronavirus disease 2019 (COVID-19)

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