Trial intelligence / Profile preview

IMPACT-RHD: Oral Azithromycin vs Intramuscular Penicillin for RHD Prevention

NCT07625228Not yet recruiting

Sponsor
Ladoke Akintola University of Technology
Start
Jan 2027
Primary completion
Dec 2030
01

Overview

Randomised, open-label trial of azithromycin in rheumatic heart disease (RHD) and rheumatic fever (RF) (2 arms), sponsored by Ladoke Akintola University of Technology. Primary endpoints: Recurrence of acute rheumatic fever at 24 months and Progression of valvular cardiomyopathy at 24 months. Planned start Jan 2027; status: not yet recruiting.

02

Drugs

azithromycin
03

Conditions

rheumatic heart disease (RHD)rheumatic fever (RF)

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