Trial intelligence / Profile preview

[177Lu]Lu-A9-0631 and [225Ac]Ac-A9-0642 in GRPR+ Tumors

NCT07661641Phase 1Recruiting

Sponsor
Alpha-9 Oncology
Start
Jul 2026
Primary completion
Dec 2028
Countries
1
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Overview

Phase 1, open-label trial of [177Lu]Lu-A9-0631 and [225Ac]Ac-A9-0642 in breast cancer, prostate cancer (PCa), colorectal cancer (CRC) and 1 more (2 arms), sponsored by Alpha-9 Oncology. Primary endpoints: Incidence of Adverse Events by Frequency, Duration, and Severity, Number of Patients with Dose-Limiting Toxicities at 28 days and 1 more. Started Jul 2026; status: recruiting.

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Drugs

[177Lu]Lu-A9-0631[225Ac]Ac-A9-0642
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Conditions

breast cancerprostate cancer (PCa)colorectal cancer (CRC)solid tumor

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