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Effects of General vs Spinal-Epidural Anesthesia on Ferroptosis and Mitochondrial Peptides in Kidney Transplant

NCT07678073Recruiting

Sponsor
Gaziantep University
Start
Mar 2026
Primary completion
Oct 2026
Countries
1
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Overview

Open-label trial of sevoflurane and bupivacaine in end stage renal disease (ESRD) (2 arms), sponsored by Gaziantep University. Primary endpoint: Serum ferroptosis-related biomarkers (Fe, TFRC1, GPX4, MDA, ACSL4) and mitochondrial-derived peptides (humanin and MOTS-c). Started Mar 2026; status: recruiting.

02

Drugs

sevofluranebupivacaine
03

Conditions

end stage renal disease (ESRD)

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