Trial intelligence / Profile preview

Prime REMIX: LD-TBI and CAR T-cell Therapy in Relapsed/Refractory DLBCL and Multiple Myeloma

NCT07725406Phase 1Recruiting

Sponsor
Weill Cornell Medicine
Start
Nov 2026
Primary completion
Aug 2028
Countries
1
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Overview

Phase 1, randomised, open-label trial of lisocabtagene maraleucel, axicabtagene ciloleucel and ciltacabtagene autoleucel in diffuse large B-cell lymphoma (DLBCL) and multiple myeloma (MM) (10 arms), sponsored by Weill Cornell Medicine. Primary endpoint: Incidence of Dose-Limiting Toxicities at Day 28. Started Nov 2026; status: recruiting.

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Drugs

lisocabtagene maraleucelaxicabtagene ciloleucelciltacabtagene autoleucel
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Conditions

diffuse large B-cell lymphoma (DLBCL)multiple myeloma (MM)

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