Trial intelligence / Profile preview

Effects of Sirolimus on Middle Aged Asymptomatic ApoE4 Carriers

NCT07728175Phase 1Recruiting

Sponsor
University of Missouri
Start
Dec 2026
Primary completion
Dec 2027
Countries
1
01

Overview

Phase 1, randomised, double-blind trial in Alzheimer's disease (AD) comparing Sirolimus with Placebo (2 arms). Primary endpoint: Change in Cerebral Blood Flow at 4 weeks. Planned start Dec 2026; status: recruiting.

02

Drugs

sirolimus
03

Conditions

Alzheimer's disease (AD)

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