Trial intelligence / Profile preview

Psilocybin for Changes in Self-awareness

NCT07732166Phase 1Recruiting

Sponsor
Pontifical Catholic University of Rio de Janeiro
Start
Apr 2026
Primary completion
Aug 2027
Countries
1
01

Overview

Phase 1, randomised, double-blind trial of psilocybin in major depressive disorder (MDD), obsessive compulsive disorder (OCD) and anxiety disorder (2 arms), sponsored by Pontifical Catholic University of Rio de Janeiro. Primary endpoint: Changes in global metacognitive judgment using the Computerized Success-Failure Manipulation Paradigm at 1 week. Started Apr 2026; status: recruiting.

02

Drugs

psilocybin
03

Conditions

major depressive disorder (MDD)obsessive compulsive disorder (OCD)anxiety disorder

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