Trial intelligence / Profile preview

PATHS-T2D: Physiologic and Pharmacologic Responses to Orforglipron

NCT07739537Phase 4Not yet recruiting

Sponsor
Massachusetts General Hospital
Start
Oct 2026
Primary completion
Sep 2029
01

Overview

Phase 4, open-label trial of orforglipron in type 2 diabetes mellitus (T2DM) and prediabetes (2 arms), sponsored by Massachusetts General Hospital. Primary endpoints: Physiologic characterization by MMTT at 1 day and The acute drug challenges at 12 days. Planned start Oct 2026; status: not yet recruiting.

02

Drugs

orforglipron
03

Conditions

type 2 diabetes mellitus (T2DM)prediabetes

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